{"product_id":"dutch-cycle-mapping-complete","title":"DUTCH CYCLE MAPPING+ Complete","description":"\u003cp\u003e\u003cstrong\u003eDUTCH Complete\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHOW DOES DUTCH COMPARE TO OTHER HORMONE TESTS?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDUTCH vs. Saliva Testing\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e– While the free cortisol pattern in saliva has clinical value, there is a significant missing piece to surveying a patient’s HPA-Axis function with saliva testing – measuring cortisol metabolites. To properly characterize a patient’s cortisol status, free and metabolized cortisol should be measured to avoid misleading results when cortisol clearance is abnormally high or low. Likewise with sex hormones, measuring estrogen and androgen metabolites gives a fuller picture for more precise clinical diagnosis of hormonal imbalances and HRT monitoring.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDUTCH vs. Serum Testing\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e– While the most universally accepted testing method (due to the availability of FDA-cleared analyzers that are reliable and inexpensive), serum testing is lacking in some areas. Adrenal hormones cannot be effectively tested in serum because free cortisol cannot be tested throughout the day. There is also a lack of extensive metabolite testing (especially for cortisol and estrogens).\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDUTCH vs. 24-Hour Urine Testing\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e– There are two primary drawbacks to 24-hour urine testing of hormones. First, the collection is cumbersome, and as many as 40% of those who collect, do so in error (Tanaka, 2002). Secondly, dysfunction in the diurnal pattern of cortisol cannot be ascertained from a 24-hour collection. Some providers add saliva for daily free cortisol. DUTCH eliminates the need for two tests.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWHY USE DUTCH? The Easiest Patient Collection:\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003ePatients collect just four or five dried urine samples over a 24-hour period. Dried samples are stable for several weeks making them convenient to ship worldwide.\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eAnalytical and Clinical Validation:\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003ePrecision Analytical’s testing methods go through a rigorous validation process to verify accuracy, recovery, and linearity. We pride ourselves in relentlessly pursuing the most accurate and precise techniques available for testing.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEffective HRT Monitoring:\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003eDUTCH testing was designed to be optimally effective for most forms of hormone replacement therapy. Unique methods are used for improved monitoring of oral progesterone and vaginal hormones.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWHAT DAYS OF THE MONTH DO I COLLECT?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCycling Premenopausal Women\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003eBegin collection between days 19 and 22 of a 28-day cycle. For longer cycles, add the number of days you usually go beyond 28 days. In a similar manner, subtract if your cycles are shorter (example: collect days 17-20 for a 26 day cycle). You may collect any day if only ordering the\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eDUTCH Adrenal\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003eor\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eDUTCH OATs\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp\u003eFor irregular cycles or non-cycling (ablation or uterus removed), watch the irregular cycle collection video in the video library at dutchtest.com\/videos for suggestions on collecting.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMen \u0026amp; Non-Cycling or Postmenopausal Women\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003eCollect any day.\u003c\/p\u003e\n\u003cp\u003eFor some women, testing reproductive hormones (progesterone, estrogen, etc.) on a single day is sufficient. In other scenarios, the clinical picture cannot be properly captured without “mapping” out the hormonal pattern throughout their menstrual cycle.\u003c\/p\u003e\n\u003cp\u003eThe expected pattern of hormones shows relatively low estrogen levels early in the cycle, a surge around ovulation and modest levels in the latter third of the cycle (the luteal phase). Progesterone levels, on the other hand, stay relatively low until after ovulation. After ovulation, levels ideally increase (\u0026gt;10-fold) and then drop back down at the end of the cycle. A disruption in this cycle can leLEad to infertility or hormonal imbalance.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDUTCH Cycle Mapping\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWHEN IS DUTCH CYCLE MAPPING™ RECOMMENDED?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e Women struggling with infertility\u003c\/li\u003e\n\u003cli\u003e Women with cycling hormones and no menses\u003c\/li\u003e\n\u003cli\u003e Partial hysterectomy (ovaries intact but no uterus)\u003c\/li\u003e\n\u003cli\u003e Ablations\u003c\/li\u003e\n\u003cli\u003e Mirena IUD (no actual menstrual bleeding due to IUD but still has hormonal symptoms)\u003c\/li\u003e\n\u003cli\u003e Women with irregular cycles\u003c\/li\u003e\n\u003cli\u003e PCOS\u003c\/li\u003e\n\u003cli\u003e If the luteal phase shifts from month-to-month\u003c\/li\u003e\n\u003cli\u003e Not sure when to test due to long or short cycles\u003c\/li\u003e\n\u003cli\u003e Women whose hormonal symptoms tend to fluctuate throughout the cycle\u003c\/li\u003e\n\u003cli\u003e PMS, mid-cycle spotting, migraines, etc.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eWHEN IS DUTCH CYCLE MAPPING™ NOT NEEDED? (DUTCH COMPLETE™ IS SUFFICIENT)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e Postmenopausal women\u003c\/li\u003e\n\u003cli\u003e Women on birth control\u003c\/li\u003e\n\u003cli\u003e Women with cycles that follow the expected pattern\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow to Collect-DUTCH Complete\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eComplete all information on each collection device.\u003c\/li\u003e\n\u003cli\u003eSaturate the filter paper by urinating directly on it OR use a clean cup and dip the filter paper.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eLeave the collection device open to dry for at least 24 hours.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eOnce dry, close each collection device. Place all devices in the resealable plastic bag and return in the provided envelope. Be sure to include the completed requisition form (required) and the payment card (if needed).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow to Collect Urine-Cycle Mapping\u003cbr\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eComplete all information on each urine collection device. Fill in the day of cycle and date of collection with pen (not a gel pen).\u003c\/li\u003e\n\u003cli\u003eCollect your samples with your first morning void\/urination. Saturate the filter paper by urinating directly on it OR urinating into a clean cup and dip the filter paper for 5 seconds.\u003c\/li\u003e\n\u003cli\u003eLeave each sample open to\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003edry for at least 24 hours\u003c\/strong\u003e.\u003c\/li\u003e\n\u003cli\u003eOnce dry, close each collection device and conveniently store in the kit box until you are done collecting all samples.\u003c\/li\u003e\n\u003cli\u003eContinue collecting according to your cycle schedule. Once ALL samples are completely dry, place them in the enclosed plastic bag and seal.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cstrong\u003eHow to Return\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eUPON COMPLETION\u003c\/strong\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eAfter drying the urine collection devices, make sure each sample is clearly labeled.\u003c\/li\u003e\n\u003cli\u003ePlace the urine collection devices in the resealable plastic bag and store in the test kit box.\u003c\/li\u003e\n\u003cli\u003eCut out the completed collection schedule from pages 6, 8, or 10.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cstrong\u003eSHIPPING INFORMATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003ePlace the entire test kit box, the completed collection schedule, and requisition form inside the return envelope.\u003c\/li\u003e\n\u003cli\u003eAffix the prepaid label or postage, if applicable. Return using the appropriate carrier.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e*Not available in NY, NJ , and RI*\u003c\/strong\u003e\u003c\/p\u003e","brand":"Precision Analytical","offers":[{"title":"Default Title","offer_id":53307824963881,"sku":null,"price":799.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/brighterlifelabs.com\/products\/dutch-cycle-mapping-complete","provider":"Brighter Life Labs","version":"1.0","type":"link"}