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GI Effects® Fundamentals Profile-Genova Kit

GI Effects® Fundamentals Profile-Genova Kit

Regular price $469.00 USD
Regular price Sale price $469.00 USD
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Note: This is a home collection test kit that will be mailed to you. NOT to be used for children under the age of 2. This is a three day collection kit.

Fasting Required:
Genova Diagnostics
14-21 business days
Note: Result turnaround times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.

Special Instructions:
Ship to lab Monday-Friday and avoid US holidays which may cause delays. Specimen MUST be shipped within 24 hours of final collection. 4 weeks before collection: Wait at least 4 weeks from colonoscopy or barium enema before beginning the test. 2 - 4 weeks before collection: If taking antibiotics, antiparasitics, antifungals, or probiotic supplements (acidophilus, etc.) it is recommended that you wait a minimum of 14 days after your last dose before beginning the test; 28 days may be preferred after antibiotics have been utilized. 14 days before collection: For H. pylori add-on testing, discontinuation of PPIs, antibiotics, and bismuth is recommended. 2 days before collection: Unless directed otherwise by your physician, discontinue aspirin and other NSAIDs (i.e. ibuprofen), rectal suppositories, enemas, activated charcoal, bismuth, betaine HCI, digestive enzymes, antacids, laxatives, mineral oil, castor oil, and bentonite clay.
The GI Effects Fundamentals stool profile offers valuable insight into digestive function, intestinal inflammation, and the intestinal microbiome. Optional add-on tests allow the clinician to choose pertinent markers for each patient, including parasitology and others. The core biomarkers from the GI Effects Fundamentals Profile are reported using the DIG framework, providing key clinical information for three main gastrointestinal functional areas:
Pancreatic Elastase-1 is a marker of exocrine pancreatic function. Products of Protein Breakdown are markers of undigested protein reaching the colon. Fecal Fat is a marker of fat breakdown and absorption.
Calprotectin is a marker of neutrophil-driven inflammation. Produced in abundance at sites of inflammation, this biomarker has been proven clinically useful in differentiating between Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS). Eosinophil Protein X is a marker of eosinophil-driven inflammation and allergic response. Fecal Occult Blood detects hidden blood.
Gut Microbiome:
Metabolic indicators demonstrate specific and vital metabolic functions performed by the microbiota. These include: Beneficial Short–Chain Fatty Acids (SCFA), including n–Butyrate, are fermentation products produced by bacterial action on fiber and resistant starch. N-butyrate is the primary fuel source for colonocytes. Beta-glucuronidaseis an enzyme produced by bacteria that relates to the metabolism and detoxification of certain substances. Bacteria and mycology cultures, demonstrate the presence of specific beneficial and pathogenic organisms. Bacteria and mycology sensitivities are provided for pathogenic or potentially pathogenic organisms that have been cultured. The report includes effective prescriptive and natural agents.
Analytes Reported:
  • Bacteriology Culture, aerobic
  • Bacteriology Culture, anaerobic
  • Beta-Glucuronidase
  • Calprotectin
  • Eosinophil Protein X (EPX)
  • Fecal Fats
  • Occult Blood
  • Pancreatic Elastase
  • ParaPCR
  • Parasite Identification, Conctr. Prep
  • Parasite Identification, Trichrome Stain
  • Short Chain Fatty Acids
  • Yeast Culture

Additional Biomarkers Available for add-on at additional cost:
Parasitology Diarrhea Present, Enterohemorrhagic E. coli Shiga-like toxin Campylobacter specific antigen EIA Secretory IgA Macroscopic/Direct Exam for Parasites Helicobacter pylori Stool Antigen EIA Clostridium difficile EIA KOH Preparation for Yeast Zonulin Family Peptide, Stool
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